Cerebral sinus thrombosis in patients with inflammatory bowel disease: A case report

Table 1 Clinical characteristics of ulcerative colitis patients with cerebral venous thrombosis

Reference	Sex	Age	IBDactivity	IBDlocation	IBDduration	CNS circulationinvolved	Outcome	Coagulation studies	Miscellaneous
Gonera et al.[20]	F	30	Active	Pancolitis	-	SSS	Recovered	Functional	Deep
								APC resistance,	venous
								hyperhomocysteinemia	thrombosis
Tsujikawa et al.[21]	M	27	Active	Recto-sigmoid	9 yr	SSS	Recovered	-	-
Derdeyn et al.[22]	F	26	Remission	-	-	Isolated cortical	Residual	-	Deep
						vein (sylvian vein)			venous
									thrombosis
Das et al.[23]	M	31	Active	Pancolitis	-	SSS	Death	-	Pulmonary
									emboli
									at autopsy
	M	20	Active	Pancolitis	2 yr	SSS and superficial	Death		Pulmonaryemboli
						cerebral veins			at autopsy
Philips et al.[24]	F	35	-	-	-	SSS, TS, StS		-	-
						Recovered
	F	14	-	-	-	SSS, vein of labbe	Recovered	-	-
Srivastava et al.[25]	M	29	Remission	-	6 mo	SSS, left sigmoid	Recovered	No abnormality found	-
						sinus
Papi et al.[26]	F	33	Active	-	First attack	Superior, inferior	Residual	Lupus	Impending
						long. Sinuses		anticoagulant positive	megacolon
Kao et al.[27]	-	14	-	-	3 yr	SSS, vein of labbe	Residual		ANCA positive
	-	7	-	-	4 mo	Transverse and	Residual	Elevated	-
						sigmoid sinuses		anticardiolipin
								antibody
	-	20	-	-	6 yr	SSS and	Recovered	Elevated	-
						transverse sinuses		anticardiolipin
								antibody
	-	13	-	-	18 mo	SSS, cortical	Recovered	Hyperhomocysteinemia,	-
						veins, TS, SS		heterozygous for
								prothrombin gene
Kiff et al.[28]	F	26	Active	Pancolitis	First attack	Straight sinus	Death	-	In the
						and great cerebral			postpartum
						vein of Galen			period
Markowitz et al.[30]	M	14	Active	Pancolitis	9 mo	Left sigmoid	Residual	-	-
						and lateral sinuses
Borda et al.[31]	M	23	Active	-	-	All major	Death	-	Pulmonary
						venous sinuses			emboli,
									renal vein
									thrombosis
Schneiderman et al.[32]	F	12	Active	-	-	Straight sinus,	Death	-	-
						vein of galen
Lam et al.[33]	F	28	-	Pancolitis	-	-	Residual	-	-
Averback et al.[34]	F	25	Remission	-	-	-	Death	-	-
Yerby et al.[35]	M	28	Remission	Pancolitis	-	-	Recovered	-	10 yr after
									proctocolectomy
Bewermeyer et al.[36]	F	35	Active	-	-	Inf. Sagittal	Death	-	-
						sinus, StS
Gil-Peralta et al.[37]	F	48	Active	-	-	Superficial	Death	-	-
						cortical veins
Musio et al.[29]	M	24	-	Pancolitis	2 yr	SSS	Recovered	-	-
Present study	M	53	Active	Pancolitis	First attack	SSS	Death	F V Leiden	Nosocomial
								heterozygous	pulmonary
								mutant	infection,
									sepsis
Total	F:11	Mean:	Active:	Pancolitis:	-	-	-	-	-
	M: 9	25.6 yr	12 remission:4	10 RS: 1

M: male, F: female, SSS: superior sagittal sinus, TS: transverse sinus, SS: sigmoid sinus, StS: straight sinus, APC: activated protein C.