Lack of specific association between gastric autoimmunity hallmarks and clinical presentations of atrophic body gastritis

Table 2 Demographic, clinical, biochemical and histological findings in 140 patients with atrophic body gastritis (ABG)

.	IFA positive	IFA negative	P
Demographic and clinical features
Patients (%)	49 (35)	91 (65)
Gender (M/F)	18/31	31/60	NS
Age, yr, median (range)	58 (26-83)	55 (22-78)	NS
Pernicious anemia, n (%)	32 (65.3)	33 (36.3)	P = 0.0013
Iron deficiency anemia, n (%) 12 (24.5)		45 (49.4)	P = 0.0042
Dyspepsia, n (%)	5 (10.2)	13 (14.3)	NS
Associated autoimmune	10 (20.4)	15 (16.5)	NS
disease, n (%)
Biochemical features and gastric autoantibodies
PCA positive1, n pts (%)	39 (80)	70 (77)	NS
Gastrin (pg/ mL)	500 (55-2.500)	405 (49-2.700)	P = 0.0579
median (range)
Pepsinogen I (ng/mlL)	5 (0-72)	10 (0-84)	P = 0.0027
median (range)
Histological features
Body atrophy score	2.67 ± 0.09	2.28 ± 0.08	P = 0.0028
(mean ± SE)
Antral atrophy, n (%)	10 (20.4)	26 (28.6)	NS
Antral atrophy score	1.2 ± 0.13	1.42 ± 0.1	NS
(mean ± SE)
Antrum spared, n (%)	22 (44.9)	37 (40.7)	NS
H pylori positive2, n (%)	37 (76)	70 (77)	NS

¹Parietal cell antibodies,

²sum of H pylori positive patients at histology and at serology. NS = not significant.