Comparison of childhood hepatic malignancies in a hepatitis B hyper-endemic area

Table 2 Summary of clinical characteristics, laboratory investigations, cirrhosis, primary resectability, chemotherapeutic conversion and tumor recurrence in children with hepatic malignancies

	Hepatocellular carcinoma	Hepatoblastoma	P
Mean age in yr (SD)	10.6 (3.3)	2.5 (3.5)	< 0.0012
Median age in yr	11.3	1
Sex			0.42
Male	56	38
Female	17	16
Serum alpha fetoprotein			0.2991
≤20 ng/mL	1	3
>20 ng/mL	54	34
Hepatitis B carrier			< 0.001
Yes	56	4
No	0	31
Child’s classification			0.673
A	41	29
B	14	8
Liver cirrhosis			< 0.001
Yes	26	0
No	14	30
Primary complete resection			0.285
Yes	12	13
No	61	41
Tumor recurrence after resection			0.0411
Yes	7	2
No	5	11
Complete resection after chemotherapy			< 0.001
Yes	0	12
No	14	6

¹Fisher’s exact test and

²Two samples, independent-groups t test.