Preventative effects of a probiotic, Lactobacillus salivarius ssp. salivarius, in the TNBS model of rat colitis

Figure 2 Histological sections of colonic mucosa from colitic rats 1 wk after TNBS instillation stained with hematoxylin and eosin. A: Non-colitic group showing the normal histology of the rat colon (original magnification ×20); B: TNBS control group showing complete destruction of the mucosa, which has been substituted by inflammatory granulation tissue. There is evident edema and intense diffuse transmural inflammatory infiltrate (original magnification ×100); C: L. salivarius ssp. salivarius treated group showing amelioration of the inflammatory process and ‘restoration’ of the mucosal tissue with presence of mucin replenished goblet cells (original magnification ×100).