Association of polymorphism of tumor necrosis factor-alpha gene promoter region with outcome of hepatitis B virus infection

Table 4 TNF-238 polymorphism and allele frequencies in chronic HB, asymptomatic carrier and self-limited groups

Group	n	Genotype (%)					Alleles (%)1
		GG	GA	AA	χ2	P	G	A
Chronic HB group	433	402 (90.7)	41 (9.3)	0 (0.00)	845 (95.4)	41 (4.6)
Carrier group	208	187 (89.0	23 (11.0)	0 (0.00)	0.464 (to patient)	0.496 (to patient)	397 (94.5)	23 (5.5)
Self-limited group	244	232 (95.1)	12 (4.9)	0 (0.00)	4.157 (to patient)	0.041 (to patient)	476 (97.5)	12 (2.5)
					5.776 (to carrier)	0.016 (to carrier)

¹χ² = 3.99, P = 0.046. Hardy–Weinberg χ² = 0.155, P = 0.69.