In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells

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Sep 7, 2005 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Gastric Cancer

World J Gastroenterol. Sep 7, 2005; 11(33): 5136-5141
Published online Sep 7, 2005. doi: 10.3748/wjg.v11.i33.5136

Table 1 Effect of chitosan nanoparticles on cell cycle of MGC803 cells (mean±SD)

Concentration (μg/mL)	Cell cycle phase distribution (%)			AI
Concentration (μg/mL)	G₀/G₁	S	G₂/M	AI
0	71.8±1.3	17.3±0.9	9.5±0.2	1.7±0.2
25	70.5±0.8^b	16.7±1.1	8.3±2.1	3.9±0.6^b
50	69.4±0.6^b	15.9±0.6	7.4±0.3	6.8±0.3^b
75	67.3±0.4^b	13.2±2.3	12.3±0.5	7.6±0.4^b
100	51.5±1.3^b	23.5±1.1	15.2±3.1	9.9±0.5^b

AI: apoptotic incidence;

^bP<0.01 vs control.

Citation: Qi LF, Xu ZR, Li Y, Jiang X, Han XY. In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells. World J Gastroenterol 2005; 11(33): 5136-5141
URL: https://www.wjgnet.com/1007-9327/full/v11/i33/5136.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i33.5136