Recurrent chromosomal rearrangements at bands 8q24 and 11q13 in gastric cancer as detected by multicolor spectral karyotyping

Table 3 Recurrent breakpoints and partners in gastric cancer cells defined by SKY analysis

Translocation	Number of	Candidate	Partner breakpoints involved in chromsomal translocations or deletions1
breakpoint	breakpoints	genes	Common	Single
8q24.1	30	MYC	11q13 [3], 13q14 [4]	1p22, 1p32-36.1, 1p34, 1p36.1, 1p36.3, 1q42, 2p11.2, 3p21.3, 7q22,
				7q32, 7q36, 8p23, 9p13, 9q22, 10p13, 10q11.2, 17q11.2, 17q23,
				18q21, 20p11.2, 20q11.2, 20q13.1, Xq28, deletion
11q13	26	FGFR4	8q24.1 [3], 8q24.3 [3],	1p13, 2p21, 7p15, 7q11.1, 7q22, 7q36, 7?, 9q13, 9q22, 11q23, 12q22,
				13p11.2, 14q24, 17q25, 19q13.3
		FGF3	3q24-25 [2], 17q11.2 [2],
		CCND1	deletion [2]
20q11.2	14	Unknown	18q11.2 [2]	2p11.2, 2q33, 7p11.2, 7q22, 7q32, 8p11.2, 8q24, 11p13, 13q12,
				17q23, 18q21.1, deletion
1p32-36.3	12	RUNX3	8q24 [4]	2p11.1, 2q21, 9q32, 16q22, 17q21, 20q13.1, Xp11.4, deletion
13q14	12	RB	8q24.1 [3]	1q44, 3p13, 4q12, 7q36, 8q13, 13q22, 18q21, 22p11.2, deletion
17q11.2	12	ERBB2	11q13 [2]	3p26, 4q12, 8p23, 8q24, 11q25, 12p11.2, 14p11.2, 16q22, Xq22, deletion
7q32	11	MET	deletion [2]	3p26, 5q13, 8q22, 8q24, 9q22, 12q21, 17q23, 20q11.2, Xq13
18q21	11	BCL2	None	1q32, 2p23, 3p21.3, 4q31.1, 8q24.1, 10q22, 13q14, 14q24, 20q11.2, deletion
17q23	10	Unknown	11q25 [2]	3p21, 4q33, 5?, 7q32, 8q24.1, 13q32, 20q11.2, 21q22
10q22	9	KSAM	deletion [2]	4q12, 6p25, 8p23, 9p13, 15q15, 15q22, 18q21
18q11.2	9	Unknown	20q11.2 [2],deletion [2]	3q21, 6q12, 6q21, 19q13.1, Xq22

¹The number of breaks are indicated.