Recurrent chromosomal rearrangements at bands 8q24 and 11q13 in gastric cancer as detected by multicolor spectral karyotyping

Table 2 Karyotypes according to SKY analysis on 7 patients with advanced gastric cancer and carcinomatous peritonitis

Case number.	Age/Sex	Origin1	Histologic grade2	G-banding and SKY
1	52/M	AS	Poor	89, XX, der (1) t (1;13) (q44;q14), t (1;2) (p36.3;p11.1), +der (1) t (1;2), +der (1) t (1;8) (p22;q24),
				+der (1) t (1;8) (p22;q24), +der (1) t (1;12) (q32;q13) del (1) (p32), +2, +2, +3, +4, +4, +del (5) (q13),
				+6, +6, +6, +7, +7, +7,
				der (8;8) (8pter→8q24.1::8p23→8q24.1::17q23→17qter), +der (8) t (8;11) (q24.1;q13), +del (8) (p11.2),
				+del (8) (p11.2), +9, +9, +i (9q), del (10) (q24), +der (10) t (8;10) (q24.1;q11.2),
				+der (10) t (8;10) (q24.1;q11.2), +inv (10) (p15.1q21), +11, +11, +12, +14, i (15q),
				i (15q), +16, +16, +17, del (18) (q11.2), +der (18) t (10;18) (p11.2;p11.2),
				+der (18) t (10;18) (p11.2;p11.2), +der (18) t (10;18) (q22;q21), +der (18) t (10;18) (q22;q21), +19, +19,
				+20, +20, +20, +20, +20, +20, -21, -21, +22
2	72/M	AS	Poor	47, XY, +X, -3, del (13) (q14), +mar
3	63/M	AS	Poor	54, der (X) t (X;3) (q24;q21), Y, +2, +del (4) (q21), +der (4) (4p15→4q12::17q11.2→17qter), +del (5) (q13),
				der (6) t (Y;6) (q11.2;p21.1), t (7;16) (q36;q22), der (11) t (9;11) (q13;q13), +del (11) (q13), +11, del (12)
				(p11.2), der (13) t (8;13) (q13;q14), +15, +16, -21, -21, +22, +22
4	56/M	AS	Signet	46, X, -Y, +der (1) t (?;1;?) (?::1p13→1q21::?), t (2;20;8) (p11.2;q11.2;q24.1),
				t (2;20;8) (p11.2;q11.2;q24.1), +2, +2, der (3) (3qter→3p13::7?→7?::11q13→11qter), del (3) (p23) (q25),
				-4, -4, +del (5) (q13), +del (5) (q11.2), del (6) (q11),
				+der (6) (6p21.1→6q21::18q11.2→18qter), dic (7;11) (q11.2;p15), del (9) (p11), del (10) (p11.2),
				del (10) (p11.2), +10,
				der (11) t (?;11;?) (?::11p13→11q23::?), der (11) (2pter→2p11.2::11q12→11p11.2::7q11.2→7q32::
				17q23→17qter),
				der (11;20) (20pter→20q11.2::11p13→11q23::11q13→11q14::7q31→7q36::13q14→13qter),
				del (12) (q13), del (12) (q22), der (13) t (X;13) (p11.2;p11.2), der (13) (3pter→3p13::13p13→13q14::18q21
				→18qter), -14, -15, del (16) (q22), add (17) (p11.2), add (18) (q21.3), -18, -19, +20,
				der (21) t (17;21) (q23;q22), der (21) (7pter→7p11.2::21p13→21q22.1::hsr::21q22.1→21qter), -22
5	55/M	AS	Signet	50, add (X) (p22.3), Y, +8, +9, +16, +18
6	37/M	AS	Poor	69, der (X) (Xpter→Xq22::18q11.2→18q21::4q31.1→4qter),
			Signet	der (X) (Xpter→Xq22::18q11.2→18q21::4q31.1→4qter), -Y, +der (1) t (1;12) (q25;q13),
				+del (1) (p22), del (2) (q23), del (2) (q23), +der (2) t (1;2) (q23;q21), +der (2) t (1;2) (q23;q21),
				del (3) (p21), +del (3) (p13), +del (3) (q11.2), +5, +5, der (6) t (6;18) (q12;q11.2), -6, +7, +7, +der (8)
				(5qter→5q31::8p11.2→8q24.1::13q14→13qter),
				+der (8) (5qter→5q31::8p11.2→8q24.1::13q14→13qter), +der (10) t (4;10) (q12;q22),
				+der (10) t (4;10) (q12;q22), +der (11) t (7;11) (q22;q23),
				+der (11) t (11;17) (q25;q11.2), +12, der (13) t (6;13) (p21.1;p11.2), -13, der (14) t (14;17) (p11.2;q11.2),
				der (14) t (14;17) (p11.2;q11.2), +15, +15, +16, +16, der (17) t (X;17) (q22;q11.2),
				der (17) t (X;17) (q22;q11.2), +18, +18, +20, +21, +der (21) t (X;21) (q22;p11.2)
7	73/F	AS	Poor	67, X, del (X) (q26), der (1) (1qter→1p22::11?→11?::8?→8?::22q11.2→22qter), der (1) (1?→1?::15?
			Signet	→15?::1?→1qter), der (1) (9pter→9p13::1p12→1q32::9q22→9qter), -2, -5,
				+der (7) t (7;9) (q32;q22), +der (7) t (7;9) (q32;q22), +der (7) t (7;20) (q22;q11.2),
				+der (7) t (7;20) (q22;q11.2), t (8;14) (q13;p13), +der (8) t (8;14), t (6;8) (p11.2;p21), +8, -9,
				+der (10) t (2;10) (p13;q24), +11, -12, +der (14) (20qter→20q13.1::
				14p11.2→14q24::11q13→11qter),
				+der (14) t (3;14) (p21;q13), +14, +15, +16, +17, +18, +18, +18, +18,
				+der (18) t (18;20) (q11.2;q11.2), +19, +20, +21, +21, +22, +der (22) t (1;22) (p22;p11.2)

¹AS: ascitic fluid. ²Poor: Poorly differentiated adenocarcinoma; Signet: signet ring cell carcinoma.