Gene expression in rats with Barrett’s esophagus and esophageal adenocarcinoma induced by gastroduodenoesophageal reflux

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Sep 7, 2005 (publication date) through Nov 4, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Esophageal Cancer

World J Gastroenterol. Sep 7, 2005; 11(33): 5117-5122
Published online Sep 7, 2005. doi: 10.3748/wjg.v11.i33.5117

Table 1 Different expressions of functional genes in BE and EA

Functional genes	Number	Upregulated	Downregulated
Oncogenes and tumor	23	13	10
suppression genes
Ion channel and transporters	26	13	13
Cell cycle proteins	13	4	9
Extra-pressure reaction proteins	20	8	12
Cell regulatory proteins	15	5	10
Cell apoptosis-related proteins	19	11	8
DNA synthesis, repair,	20	6	14
recombinant factors
DNA binding, transcription factors	23	7	16
Cell receptors	23	7	16
Immunity-related proteins	29	12	17
Cell signal transducing proteins	28	9	19
Metabolism-related proteins	29	17	12
Total	268	112	156

Citation: Cheng P, Gong J, Wang T, Chen J, Liu GS, Zhang R. Gene expression in rats with Barrett’s esophagus and esophageal adenocarcinoma induced by gastroduodenoesophageal reflux. World J Gastroenterol 2005; 11(33): 5117-5122
URL: https://www.wjgnet.com/1007-9327/full/v11/i33/5117.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i33.5117