MUC1 and MUC5AC mucin expression in liver fluke-associated intrahepatic cholangiocarcinoma

Table 3 Expressions of MUC1 and MUC5AC apomucins in ICC in relation to patients’ cancer histopathology and clinical staging

Variables	MUC1		P	MUC5AC		P
	Low	High		Low	High
Age (yr)	53	34	0.894	41	46	0.065
≤56	26	17		15	27
>56	27	17		26	19
Gender	53	34	0.698	41	46	0.058
Male	34	24		32	26
Female	19	10		9	20
Histological grading	43	24	0.575	34	33	0.095
Papillary	13	7		11	9
Well-diff.	18	8		9	17
Moderately diff.	5	6		6	5
Poorly diff.	7	3		8	2
Tumor size	51	31	0.964	38	44	0.502
≤5 cm	15	9		13	11
>5 cm	36	22		25	33
Staging	50	32	0.94	39	43	0.008
I-III	8	5		6	7
IVA	6	5		10	1
IVB	36	22		23	35
Vascular invasion	53	34	<0.001	41	46	0.284
No	27	2		17	14
Yes	26	30		24	32
Lymphatic invasion	53	34	0.995	41	46	0.124
No	14	9	14	9
Yes	39	25		27	37
Neural invasion	53	34	0.384	41	46	0.022
No	30	16		27	19
Yes	23	18		14	24

diff. = differentiation.