GFAP and Fos immunoreactivity in lumbo-sacral spinal cord and medulla oblongata after chronic colonic inflammation in rats

Figure 1 Histopathological changes of the colon. A: After 3 d of TNBS administration, the structure of the colon was destroyed (×10); B: Numerous inflammatory cells were infiltrated in the submucosa and mucosa of the colon (×40); C: After 28 d of TNBS administration, only a few inflammatory cells were infiltrated in submucosa and mucosa of the colon (×40); D: The inflammatory cells were minimal in the colon of the rats after 3 d of saline administration (×40).