ACEI attenuates the progression of CCl4-induced rat hepatic fibrogenesis by inhibiting TGF-β1, PDGF-BB, NF-κB and MMP-2,9

Table 1 Grades of fibrosis in rat liver

Groups	4 wk						6 wk
	0	1	2	3	4	n	0	1	2	3	4	n
Mo	0	1	5	0	1	7	0	0	0	3	3	6
Pea,e	1	3	2	0	0	6	0	1	1	4	0	6
Nca,c	6	0	0	0	0	6	6	0	0	0	0	6

^aP<0.05 vs Mo;

^cP<0.05 vs Pe; ^eP<0.05 Pe (4 wk) vs Pe (6 wk). Mo: model group; Pe: perindopril group; Nc: control group.