Vitamin D receptor gene Tru9I polymorphism and risk for incidental sporadic colorectal adenomas

Table 2 Frequencies of VDR Tru9I genotypes and associations with incident sporadic colorectal adenomas (MAP study), 1994-1997

VDR Tru9I genotype	Cases (n = 171)		Controls (n = 220)			Adjusted OR1	95%CI2
	n	%	n	%
UU	144	84.2	171	77.8		1
Uu	23	13.5	45	20.4		0.88	(0.17-4.55)3
uu	4	2.3	4	1.8		0.69	(0.38-1.25)
Uu+uu	27	15.8	49	22.2		0.71	(0.40-1.25)
P-trend					0.24

¹Odds ratio;

²95% confidence interval;

³adjusted for age, sex, total energy intake, history of colon cancer in a first degree relative, nonsteroidal anti-inflammatory drug use, current smoking status, and total calcium and alcohol intake.