High concentrations of human β-defensin 2 in gastric juice of patients with Helicobacter pylori infection

Table 4 Gastric juice HBD-2 and IL-1β and -8 levels before and after anti-H pylori therapy

	Successful eradication of H pylori (n = 10)			Failed eradication (n = 4)
	Before therapy	After therapy	P	Before therapy	After therapy	P
Gastric juice
HBD1-2 levels (pg/mL)	182.2±57.6	210.1±66.4	NS	137.4±65.2	112.9±79.3	NS
Interleukin 1β levels (pg/mL)	17.7±10.2	0.5±0.3	<0.05	88.5±80.9	64.7±64.1	NS
Interleukin 8 levels (pg/mL)	22.3±2.1	12.8±1.8	<0.005	18.1±6.1	18.6±4.5	NS

¹Human b-defensin, NS: not significant.