Dynamic expression of apoptosis-related genes during development of laboratory hepatocellular carcinoma and its relation to apoptosis

Table 1 Expression of p53, bcl-2, bax, and survivin in HCC and other liver tissues

Groups	Biopsy at	Cases	p53	Bcl-2	Bax	Survivin
			Positive (%)	Positive (%)	Positive (%)	Positive (%)
Control	30th wk	13	0 (0)	0 (0)	0 (0)	4 (30.8)
	60th wk	13	0 (0)	0 (0)	0 (0)	5 (38.4)
	90th wk	13	0 (0)	0 (0)	0 (0)	5 (38.4)
Trial	30th wk	35	0 (0)	3 (8.6)	2 (5.7)	14 (40)
	60th wk	35	21 (60)bd	7 (20)	10 (28.6)ac	13 (37.1)
	HCC	35	25 (71.4)bd	14 (40)	25 (71.4)bde	19 (57.1)

^aP < 0.05,

^bP < 0.01 vs each stage control;

^cP < 0.05,

^dP < 0.01 vs experiment for 30 wk;

^eP<0.05 vs experiment for 30 wk.