Lipid peroxidation and antioxidant status in colorectal cancer

Table 1 Levels of final lipid peroxidation products–malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) in the colorectal cancer and normal colon mucosae (mean±SD).

	Variable	n	Levels of lipid peroxidation products (nmol/g tissue)
			MDA	4-HNE
Histological type/grade of	Adc.G2	60	1.97±0.39a	0.40±0.08b
colorectal cancer	Adc.G3	6	2.15±0.44d	0.44±0.10d
	Adc.muc	15	2.65±0.48fik	0.44±0.07fi
Clinical stage of colorectal cancer	II	46	1.7±0.39a	0.37±0.07a
	III	29	2.25±0.43dg	0.45±0.09dg
	IV	6	4.04±0.47fik	0.52±0.11fik
Control (normal colon mucosa)			1.39±0.15	0.29±0.03

^aP<0.05,

^bP<0.001-comparison between Adc G2 or stage II cancers and control group. ^cP<0.05,

^dP<0.001-comparison between Adc G3 or stage III cancers and control group. ^eP<0.05,

^fP<0.001-comparison between mucinous adc or stage IV cancers and control group.

^gP<0.05-comparison between Adc G2 or stage II cancers and Adc G3 or stage III cancers.

ⁱP<0.05-comparison between Adc G2 or stage II cancers and mucinous adc or stage IV cancers.

^kP<0.05-comparison between Adc G3 or stage III cancers and mucinous adc or stage IV cancers.