Effects of frying oil and Houttuynia cordata thunb on xenobiotic-metabolizing enzyme system of rodents

Table 3 Liver microsomal protein content (CYP450) and the activity of liver NADPH reductase in Sprague-Dawley rats fed with the fresh/oxidized frying oil and 0%, 2% and 5% H. cordata thunb powder diets for 4 wk (mean±SD, n = 8).

Group	Microsomal protein (mg/g liver)	CYP450 (nmol/mg protein)	NADPH reductase (nmol/mg protein)
F0	13.36±4.711	0.61±0.271	202.31±28.11
F20	15.66±0.961	0.73±0.101	228.42±30.41
F50	15.79±1.351	0.74±0.141	225.64±25.3
O0	23.74±2.54	1.63±0.75	256.03±31.12
O20	22.13±3.76	2.14±1.10	288.55±29.63
O50	22.25±2.96	2.08±0.15	234.15±25.42
ANOVA4
Dose	NS5	NS	NS
Oil	P<0.05	P<0.05	P<0.05
Dose×Oil	P<0.05	P<0.05	NS

¹Mean values significantly differ between the two oil groups (P<0.05). ^2,3Means not sharing common superscript letters significantly differ from one another by Duncan’s multiple range test for the same oil group (P<0.05).

⁴Analyzed by a two-way ANOVA.

⁵NS: No significance.