Expression and hypermethylation of p27kip1 in hepatocarcinogenesis

doi:10.3748/wjg.v11.i29.4587

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Aug 7, 2005 (publication date) through Jul 31, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 7, 2005; 11(29): 4587-4591
Published online Aug 7, 2005. doi: 10.3748/wjg.v11.i29.4587

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Figure 2 MCP of CpG islands of p27^kip1 promoter. Lane 1: marker; lanes 2, 4, 6, 8 and 10: PCR products of each case to unmethylated specific primers. Lanes 3, 5, 7, 9 and 11: PCR products of each case to methylated specific primers. In HCC19 case, only methylated DNA (M) was present. HCC88 case and L.C21 case (liver cirrhosis case) showed unmethylated statue (U). Positive control (P.C) for methylated DNA was treated with SssI methylase first, normal control (N.C) for unmethylated DNA.

Citation: Lei PP, Zhang ZJ, Shen LJ, Li JY, Zou Q, Zhang HX. Expression and hypermethylation of p27^kip1 in hepatocarcinogenesis. World J Gastroenterol 2005; 11(29): 4587-4591
URL: https://www.wjgnet.com/1007-9327/full/v11/i29/4587.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i29.4587