Impact of release characteristics of sinomenine hydrochloride dosage forms on its pharmacokinetics in beagle dogs

doi:10.3748/wjg.v11.i29.4547

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Aug 7, 2005 (publication date) through Jul 30, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 7, 2005; 11(29): 4547-4551
Published online Aug 7, 2005. doi: 10.3748/wjg.v11.i29.4547

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Figure 5 Relationship between cumulative SM•HCl percentage release in vitro f(t) and percentage absorption in vivo F(t) of the two dosage forms. S, I and R are the abbreviations for the slope, intercept and correlation coefficient for the correlation equation, respectively. Twenty-four-hour test sustained-release pellets (●) and 12-h reference sustained-release tablets (○).

Citation: Sun J, Shi JM, Zhang TH, Gao K, Mao JJ, Li B, Sun YH, He ZG. Impact of release characteristics of sinomenine hydrochloride dosage forms on its pharmacokinetics in beagle dogs. World J Gastroenterol 2005; 11(29): 4547-4551
URL: https://www.wjgnet.com/1007-9327/full/v11/i29/4547.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i29.4547