Role of interleukin 18 in acute lung inflammation induced by gut ischemia reperfusion

Figure 2 The effect of exogenous IL-18 on the ischemia/reperfusion-induced lung injury. A: IL-18 injection further remarkably enhanced the neutrophil sequestration in lung. After indicated times of reperfusion, the MPO activity was determined in lung tissue (n = 5), ^aP<0.05 vs I/R. B: Comparison of pulmonary histopathology. Lungs from IL-18-nontreated (a, for 1 h of reperfusion and b, for 3 h) or IL-18-treated (c, for 1 h and d, for 3 h of reperfusion) mice subjected to gut I/R and stained with HE. Magnification ×100.