Tetramethylpyrazine stimulates cystic fibrosis transmembrane conductance regulator-mediated anion secretion in distal colon of rodents

Figure 5 Involvement of cAMP in TMP-induced I_SC response. A: Representative recordings of I_SC response to IBM× (100 µmol/L), forskolin (10 µmol/L) without additive effect observed upon subsequent challenge of TMP (1 mmol/L); B: Effect of H₈₉ (5 µmol/L) on TMP (1 mmol/L)-induced I_SC response. Values are mean±SE; ^bP < 0.001 vs control.