Enhanced plasma ghrelin levels in Helicobacter pylori-colonized, interleukin-1-receptor type 1-homozygous knockout (IL-1R1-/-) mice

Figure 2 The total ghrelin leveThe levels in the plasma. Although neither simple lack of the IL-1 signal (spotted clear column: n = 4) nor H pylori infection alone (filled column: n = 4) was associated with any changes in the total plasma ghrelin levels as compared with the levels in the uninfected wild-type mice (clear column: n = 5), H pylori infection induced a marked increase of the total plasma ghrelin levels in the IL-1R1^-/- mice (spotted filled column: n = 6). ^aP < 0.05 vs the uninfected mice. ^bP < 0.001 vs the wild-type mice.