Colchicine sensitizes human hepatocellular carcinoma cells to damages caused by radiation

doi:10.3748/wjg.v11.i27.4237

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 21, 2005; 11(27): 4237-4240
Published online Jul 21, 2005. doi: 10.3748/wjg.v11.i27.4237

Table 2 Cell cycle analysis of human HA22T/VGH hepatocellular carcinoma cells. Cell were treated with various doses of colchicine for 24 h and analyzed by flow cytometry

Colchicine (ng/mL)	Cell cycle distribution (%)
Colchicine (ng/mL)	G₀/G₁	S	G₂+M
0	49.0 ± 1.4	24.6 ± 1.1	26.4 ± 1.0
1	51.4 ± 1.1	21.7 ± 1.4	26.9 ± 1.0
2	52.2 ± 1.5	21.5 ± 1.4	26.3 ± 0.9
4	51.6 ± 1.9	22.0 ± 1.5	26.5 ± 0.9
8	43.0 ± 2.1^a	21.7 ± 1.7	35.4 ± 1.2^b
16	17.6 ± 1.3^b	23.5 ± 1.3	58.9 ± 2.2^b

^aP < 0.05,

^bP < 0.01 vs colchicine treatment with 0 ng/mL.

Citation: Liu CY, Liao HF, Shih SC, Lin SC, Chang WH, Chu CH, Wang TE, Chen YJ. Colchicine sensitizes human hepatocellular carcinoma cells to damages caused by radiation. World J Gastroenterol 2005; 11(27): 4237-4240
URL: https://www.wjgnet.com/1007-9327/full/v11/i27/4237.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i27.4237