Copyright
©The Author(s) 2005.
World J Gastroenterol. Jul 21, 2005; 11(27): 4188-4193
Published online Jul 21, 2005. doi: 10.3748/wjg.v11.i27.4188
Published online Jul 21, 2005. doi: 10.3748/wjg.v11.i27.4188
Polymorphic site | Genotype | Number of patients | Age at onset (yr) | ||||
(n = 79, %) | <40 | ≥40 | |||||
C–318T | C/C | 63 (79.8) | 54 | 9 | |||
C/T | 14 (17.7) | 12 | 2 | ||||
T/T | 2 (2.5) | 2 | 0 | ||||
A+49G | A/A | 9 (11.4) | 8 | 1 | |||
A/G | 41 (51.9) | 35 | 6 | ||||
G/G | 29 (36.7) | 25 | 4 | ||||
G+6230A | G/G | 39 (49.4) | 35 | 4 | |||
G/A | 37 (46.8) | 30 | 7 | ||||
A/A | 3 (3.8) | 3 | 0 | ||||
(AT)n in 3'-UTR | (AT)7/(AT)7 | 41 (51.9) | 34 | 7 | |||
(AT)7/(AT)x or others | 38 (48.1) | 34 | 4 | ||||
(Continued) | |||||||
Location of lesion | Operation | Fistula | |||||
Ileocolon | Ileum | Colon | Yes | No | Presence | Absence | |
40 | 14 | 9 | 33 | 30 | 27 | 36 | |
11 | 1 | 2 | 9 | 5 | 8 | 6 | |
2 | 0 | 0 | 2 | 0 | 2 | 0 | |
7 | 2 | 0 | 5 | 4 | 5 | 4 | |
25 | 11 | 5 | 20 | 21 | 14 | 27 | |
21 | 2 | 6 | 19 | 10 | 18 | 11 | |
25 | 5 | 7 | 21 | 18 | 19 | 20 | |
25 | 8 | 4 | 22 | 15 | 18 | 19 | |
1 | 2 | 0 | 1 | 2 | 0 | 3 | |
27 | 10 | 4 | 24 | 17 | 19 | 22 | |
26 | 9 | 3 | 20 | 18 | 17 | 21 |
- Citation: Machida H, Tsukamoto K, Wen CY, Narumi Y, Shikuwa S, Isomoto H, Takeshima F, Mizuta Y, Niikawa N, Murata I, Kohno S. Association of polymorphic alleles of CTLA4 with inflammatory bowel disease in the Japanese. World J Gastroenterol 2005; 11(27): 4188-4193
- URL: https://www.wjgnet.com/1007-9327/full/v11/i27/4188.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i27.4188