Gastrin and antral G cells in course of Helicobacter pylori eradication: Six months follow up study

Table 2 Antral G cell in dyspeptic patients before and after eradication therapy-morphometric analysis on light microscopy

	H pylori +Ge	H pylori +Gne	H pylori +DU	CG1	CG2	P
	(n = 24)	(n = 7)	(n = 8)	(n = 11)	(n = 7)
G cell number (per mm2 of antral mucosa)
Before therapy	416 ± 40	405 ± 32	292 ± 20a	413 ± 61	426 ± 57	0.05a
After therapy	294 ± 32a	432 ± 18	400 ± 32b	428 ± 80	/	NS
P	0.05a	NS	0.01b	NS	/
G cell volume density (%)
Before therapy	0.48 ± 0.09	0.43 ± 0.11	0.42 ± 0.02	0.48 ± 0.03	0.44 ± 0.02	NS
After therapy	0.31 ± 0.02a	0.40 ± 0.04	0.43 ± 0.01	0.50 ± 0.03	/	NS
P	0.05	NS	NS	NS	/
Antral G/ total antral endocrine cells ratio
Before therapy	0.44 ± 0.04	0.40 ± 0.03	0.37 ± 0.05	0.44 ± 0.29	0.45 ± 0.07	NS
After therapy	0.44 ± 0.02	0.47 ± 0.07	0.41 ± 0.07	0.44 ± 0.37	/	NS
P	NS	NS	NS	NS	/

H pylori+Ge- H pylori+eradicated patients with gastritis; H pylori+Gne-H pylori+non eradicated patients with gastritis; H pylori+DU-patients with H pylori+duodenal ulcer; CG1-H pylori negative dyspeptic patients; CG2- asymptomatic volunteers; NS- P>0.05;

^aP<0.05;

^bP<0.01.