Lansoprazole prevents experimental gastric injury induced by non-steroidal anti-inflammatory drugs through a reduction of mucosal oxidative damage

Figure 4 PGE2 levels in the gastric mucosa of rats treated with indomethacin (IND, 100 µmol/kg), diclofenac (DIC, 60 µmol/kg), piroxicam (PIR, 150 µmol/kg) or ketoprofen (KET, 150 µmol/kg), either alone or in the presence of lansoprazole (LAN, 90 µmol/kg). Each column represents the mean value obtained from 6 to 8 animals ± SE (vertical lines). ^aP < 0.05 vs control values; ^cP < 0.05 between the respective values obtained in animals treated with a test NSAID alone.