Head-to-head comparison of H2-receptor antagonists and proton pump inhibitors in the treatment of erosive esophagitis: A meta-analysis

Table 7 Healing by grade at 4, 8 wk comparing standard dose of other PPIs vs omeprazole

		4-wk				8-wk
		I	II	III	IV	I	II	III	IV
Number of arms		3	3	3	1	3	3	3	1
sd PPIs	Pooled data	195/239	302/362	148/210	3/7	214/235	329/360	175/209	2/4
	Pooled rate (%)	81.6	83.4	70.5	42.9	91.1	91.4	83.7	50.0
sd omeprazole	Pooled data	190/238	315/393	132/195	3/5	214/233	345/390	159/188	1/2
	Pooled rate (%)	79.8	80.2	67.8	60.0	91.8	88.5	84.6	50.0
Summary RR		1.022	1.041	1.041	0.733	0.992	1.033	0.990	1.000
95%CI		0.936-1.116	0.973-1.113	0.914-1.186	0.250-2.147	0.938-1.048	0.985-1.084	0.927-1.057	0.213-4.694

sd: standard dose.