Copyright
©The Author(s) 2005.
World J Gastroenterol. Jul 14, 2005; 11(26): 4067-4077
Published online Jul 14, 2005. doi: 10.3748/wjg.v11.i26.4067
Published online Jul 14, 2005. doi: 10.3748/wjg.v11.i26.4067
PPIs | H2RA | |||||||
2-wk | 4-wk | 8-wk | 12-wk | 2-wk | 4-wk | 8-wk | 12-wk | |
sd PPIs vs sd H2RA | ||||||||
Number of arms | 2 | 13 | 12 | 2 | 13 | 12 | ||
Pooled data | 116/183 | 577/824 | 640/783 | 60/163 | 271/713 | 350/673 | ||
Pooled healing rate (%) | 63.4 | 70.0 | 81.7 | 36.8 | 38.0 | 52.0 | ||
Summary RR | 1.759 | 1.832 | 1.586 | |||||
95%CI | 1.398-2.213 | 1.622-2.070 | 1.438-1.749 | |||||
hd PPIs vs sd H2RA | ||||||||
Number of arms | 4 | 4 | 1 | 4 | 4 | 1 | ||
Pooled data | 150/204 | 175/201 | 72/80 | 79/211 | 106/207 | 49/81 | ||
Pooled healing rate (%) | 73.5 | 87.1 | 90.0 | 37.4 | 51.2 | 60.5 | ||
Summary RR | 1.722 | 1.623 | 1.488 | |||||
95%CI | 1.464-2.027 | 1.417-1.859 | 1.230-1.800 | |||||
sd PPIs vs hd H2RA | ||||||||
Number of arms | 2 | 2 | 2 | 2 | ||||
Pooled data | 152/235 | 208/235 | 87/234 | 155/234 | ||||
Pooled healing rate (%) | 64.7 | 88.5 | 37.2 | 66.2 | ||||
Summary RR | 1.744 | 1.336 | ||||||
95%CI | 1.442-2.110 | 1.206-1.481 | ||||||
ld PPIs vs sd H2RA | ||||||||
Number of arms | 3 | 3 | 3 | 3 | ||||
Pooled data | 187/279 | 219/279 | 120/276 | 161/276 | ||||
Pooled healing rate (%) | 67.0 | 78.5 | 43.5 | 58.3 | ||||
Summary RR | 1.605 | 1.374 | ||||||
95%CI | 1.156-2.229 | 1.081-1.744 |
- Citation: Wang WH, Huang JQ, Zheng GF, Xia HHX, Wong WM, Lam SK, Wong BCY. Head-to-head comparison of H2-receptor antagonists and proton pump inhibitors in the treatment of erosive esophagitis: A meta-analysis. World J Gastroenterol 2005; 11(26): 4067-4077
- URL: https://www.wjgnet.com/1007-9327/full/v11/i26/4067.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i26.4067