Clinical Research
Copyright ©The Author(s) 2005.
World J Gastroenterol. Jul 14, 2005; 11(26): 4067-4077
Published online Jul 14, 2005. doi: 10.3748/wjg.v11.i26.4067
Table 2 Healing rate of esophagitis by ITT at 2, 3, 4, 8, 12 wk comparing proton pump inhibitors (PPIs) with H2RA
PPIs
H2RA
2-wk4-wk8-wk12-wk2-wk4-wk8-wk12-wk
sd PPIs vs sd H2RA
Number of arms2131221312
Pooled data116/183577/824640/78360/163271/713350/673
Pooled healing rate (%)63.470.081.736.838.052.0
Summary RR1.7591.8321.586
95%CI1.398-2.2131.622-2.0701.438-1.749
hd PPIs vs sd H2RA
Number of arms441441
Pooled data150/204175/20172/8079/211106/20749/81
Pooled healing rate (%)73.587.190.037.451.260.5
Summary RR1.7221.6231.488
95%CI1.464-2.0271.417-1.8591.230-1.800
sd PPIs vs hd H2RA
Number of arms2222
Pooled data152/235208/23587/234155/234
Pooled healing rate (%)64.788.537.266.2
Summary RR1.7441.336
95%CI1.442-2.1101.206-1.481
ld PPIs vs sd H2RA
Number of arms3333
Pooled data187/279219/279120/276161/276
Pooled healing rate (%)67.078.543.558.3
Summary RR1.6051.374
95%CI1.156-2.2291.081-1.744