Natural history of major complications in hepatitis C virus-related cirrhosis evaluated by per-rectal portal scintigraphy

doi:10.3748/wjg.v11.i25.3882

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Viral Hepatitis

World J Gastroenterol. Jul 7, 2005; 11(25): 3882-3886
Published online Jul 7, 2005. doi: 10.3748/wjg.v11.i25.3882

Table 2 Relative risks of possible predictors for Child-Pugh stage A to B progression

	Classification of	Proportion of Child-Pugh	¹Relative risks
	predictor at entry	stage A to B progression, n/N (%)	Crude RR (95%CI)	²Adjusted RR (95%CI)
Sex	Female	16/34 (47.1)	1.00
	Male	31/73 (42.5)	1.47 (0.76-2.84)
Age (per 1 yr)			0.99 (0.96-1.01)
Albumin, g/dL	3.5+	25/63 (39.7)	1.00	1.00
	< 3.5	22/44 (50.0)	1.49 (0.83-2.67)	0.98 (0.49-1.95)
Total bilirubin, mg/dL	< 1.0	32/69 (46.4)	1.00
	1.0+	15/38 (39.5)	1.27 (0.68-2.39)
Prothrombin time, %	100+	27/66 (40.9)	1.00
	< 100	20/41 (48.8)	1.06 (0.59-1.91)
Platelets, /mm³	10+	32/73 (43.8)	1.00	1.00
	< 10	13/32 (40.6)	1.6 (0.81-3.16)	1.40 (0.68-2.86)
Portal shunt index	Group I	11/32 (34.4)	1.51 (0.65-3.51)	1.67 (0.70-3.99)
	Group II	15/41 (36.6)	1.00	1.00
	Group III	21/34 (61.8)	2.95 (1.40-6.24)^b	2.98 (1.29-6.87)^a
			(P trend < 0.05)	(P trend: NS)
	Group (I+II)	26/73 (35.6)	1.00	1.00
	Group III	21/34 (61.8)	2.44 (1.33-4.48)^d	2.36 (1.17-4.78)^c

^aP < 0.05 vs Group II PSI,

^bP < 0.01 vs Group II PSI,

^cP < 0.05 vs Group (I+II) PSI,

^dP < 0.01 vs Group (I+II) PSI, NS: not significant. ¹RR and their 95% CI were determined by a Cox’s regression model. ²This model includes albumin, platelets, PSI. Group I, PSI ≤ 10%; Group II, 10% < PSI < 30%; Group III, 30% ≤ PSI; Group (I+II), PSI < 30%. CI: Confidence interval, RR: Relative risk, PSI: Portal shunt index, n; progression proportion, N; total proportion.

Citation: Kawamura E, Habu D, Hayashi T, Oe A, Kotani J, Ishizu H, Torii K, Kawabe J, Fukushima W, Tanaka T, Nishiguchi S, Shiomi S. Natural history of major complications in hepatitis C virus-related cirrhosis evaluated by per-rectal portal scintigraphy. World J Gastroenterol 2005; 11(25): 3882-3886
URL: https://www.wjgnet.com/1007-9327/full/v11/i25/3882.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i25.3882