Current preventive treatment for recurrence after curative hepatectomy for liver metastases of colorectal carcinoma: A literature review of randomized control trials

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Jul 7, 2005 (publication date) through Feb 27, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2005; 11(25): 3817-3822
Published online Jul 7, 2005. doi: 10.3748/wjg.v11.i25.3817

Table 3 RCTs on efficacy of neoadjuvant chemotherapy

Authors	Treatment protocol	Sample size(Tx/Ctl)	Observationtime	DFS Tx vs Ctl	OS Tx vs Ctl	Conclusions
Lorenz et al[29]	Biweekly FOLFOX regimen × 6	40 (20/20)	NA	NA	NA	Induced significant remissions
	cycles vs biweekly FOLFOX regimen × 3 cycles					without increasing morbidity
Bathe et al[30]	5-FU+leukovorin+CPT-11					Ongoing

Tx: treatment; Ctl: control; DFS: disease-free survival; OS: overall survival; NA: not available.

Citation: Wang P, Chen Z, Huang WX, Liu LM. Current preventive treatment for recurrence after curative hepatectomy for liver metastases of colorectal carcinoma: A literature review of randomized control trials. World J Gastroenterol 2005; 11(25): 3817-3822
URL: https://www.wjgnet.com/1007-9327/full/v11/i25/3817.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i25.3817