High expressions of caveolins on the proliferating bile ductules in primary biliary cirrhosis

Figure 1 Light microscopic distributions of immunohistochemically stained CAV-1 and -2 in human control liver tissue. A: CAV-1, ×100; B: CAV-2, ×100; C: double staining of CAV-1 and cytokeratin 7, ×100; D: double staining of CAV-2 and cytokeratin 7, ×100; E: CAV-1, ×400; F: CAV-2, ×400; G: double staining of CAV-1 and cytokeratin 7, ×400; H: double staining of CAV-2 and cytokeratin 7, ×400. Hematoxylin counterstain. Immunoperoxidase-positive substances showing the presence of CAV-1 and -2 are observed sparsely on hepatic sinusoidal lining cells and a little immunostaining of CAV-1 and -2 on bile ducts. A: artery, P: portal vein, C: central vein. Arrow denotes bile duct.