Expression of macrophage migration inhibitory factor is associated with enhanced angiogenesis and advanced stage in gastric carcinomas

Table 1 Relationship of MIF expression to clinicopathological characteristics of 90 patients with GCs.

	Immunohistochemical staining		P
	MIF-positive(n = 36)	MIF-negative (n = 54)
Age (yr)	61.2±13.8	57.3±14.4	0.1
Gender
Male (n = 54)	19	35	0.7
Female (n = 36)	17	19
H pylori infection
Positive (n = 69)	27	42	0.8
H pylori infection Positive (n = 69)	27	42	0.8
Negative (n = 21)	9	12
Stage
Early (n = 20)	4	16	0.04
Advanced (n = 70)	32	38
Location
Cardia (n = 13)	8	5	0.1
Non-cardia (n = 77)	28	49
Histologic subtypes
Intestinal (n = 42)	15	27	0.7
Diffuse (n = 41)	18	23
Mixed (n = 7)	3	4
Lymph node metastasis
Positive (n = 62)	28	34	0.2
Negative (n = 28)	8	20
p53 immunoreactivity
High (n = 48)	21	27	0.5
Low (n = 42)	15	27
MVD	55.1±30.1	31.3±28.8	0.0001