Interplay between nitric oxide and VIP in CCK-8-induced phasic contractile activity in the rabbit sphincter of Oddi

Figure 1 Effects of LNNA and VIPa on CCK-8-stimulated mechanical activity of rabbit SO in vitro. A: Summary of the effect of LNNA, VIPa and combined application of these substances on CCK-8-induced change of tension. Data are mean±SD, n = 6, ^aP<0.05 vs baseline. B: Summary of the effect of LNNA, VIPa and combined application of these substances on CCK-8-induced change of amplitudes. Data are mean±SD, n = 6, ^aP<0.05 vs baseline. C: Summary of the effect of LNNA, VIPa and combined application of these substances on CCK-8-stimulated contractile frequency. Data are mean±SD, n = 6, ^aP<0.05 vs baseline.