Helicobacter pylori promote gastric cancer cells invasion through a NF-kB and COX-2-mediated pathway

Figure 2 H pylori infection increases MMP-9, VEGF, and COX-2 expressions in gastric epithelial cell. MKN-45 gastric cancer cells were incubated with H pylori for 0-24 h and total cellular protein was extracted for Western blot analysis for the expression of A: MMP-9 and VEGF and B: COX-2 proteins. The blots were stripped and probed with β-actin to document equal protein loading. The experiment was performed for thrice with similar results.