Helicobacter pylori promote gastric cancer cells invasion through a NF-kB and COX-2-mediated pathway

Figure 1 Effects of H pylori infection, a cox-2 (NS398), or a NF-κB inhibitor (PDTC) on gastric cancer cell invasion. A: MKN-45 cells were treated with H pylori in the presence or absence of NS398. Cells on the lower surface of insert chamber were stained with hematoxylin for 10 min and counted under microscope with 200× magnifications. Data are presented as mean±SD of three separate experiments (P<0.05); B: MKN-45 cells were treated with H pylori in the presence or absence of PDTC (P<0.05); microscopic photos of stained migration cells: C: control; D: with H pylori; E: with H pylori and NS-398; F: control; G: with H pylori; H: with H pylori and PDTC.