Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes

Table 8 The interaction effect of the UGT1A7*3 allele and variant-211 UGT1A1 allele upon the stage of CRC.

UGT1A7*3/variant-211UGT1A1	CRC stage		OR (95%CI)	P
	C and D (n = 93)	A and B (n = 175)
Absent/absent	27 (29.0%)	118 (67.4%)	1.00
Present/absent	11 (11.8%)	17 (9.7%)	2.83 (1.19-6.72)	0.02
Absent/present	5 (5.4%)	8 (4.6%)	2.73 (0.83-9.01)	0.10
Present/present	50 (53.8%)	32 (18.3%)	6.83 (3.71-12.56)	<0.001
Expected by additive1		4.56

¹Expected OR under no-interaction additive model.