Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes

Table 5 The interaction effect of the UGT1A7*3 allele and variant-211 UGT1A1 allele upon the development of CRC.

UGT1A7*3/ variant-211UGT1A1	Number (%)		OR (95%CI)	P
	Cases (n = 268)	Controls (n = 441)
Absent/absent	145 (54.1)	302 (68.5)	1.00
Present/absent	28 (10.4)	45 (10.2)	1.30 (0.78-2.16)	0.39
Absent/present	13 (4.8)	21 (4.8)	1.29 (0.63-2.65)	0.33
Present/present	82 (30.6)	73 (16.5)	2.34 (1.61-3.40)	<0.001
Expected by additive1		1.59

¹Expected OR under no-interaction additive model.