Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes

doi:10.3748/wjg.v11.i21.3250

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Jun 7, 2005 (publication date) through Dec 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Colorectal Cancer

World J Gastroenterol. Jun 7, 2005; 11(21): 3250-3254
Published online Jun 7, 2005. doi: 10.3748/wjg.v11.i21.3250

Table 2 The comparisons between the observed percentage with the expected percentage of control subjects carrying UGT1A7*1/*2, UGT1A7*1/*3, and UGT1A7*2/*3 genotypes.

	Control subjects (n = 441)		χ²	P
	Observed percentage (%)	Expected percentage (%)¹	χ²	P
UGT1A71/2	26.5	28.9	0.081	0.960
UGT1A71/3	17.0	20.4
UGT1A72/3	7.3	7.1

¹The expected percentage was calculated by the Hardy-Weinberg equilibrium. For example, expected percentage of UGT1A7*1/*2 = 2×(frequency of UGT1A7*1/*1)^1/2×(frequency of UGT1A7*2/*2)^1/2 = 2×41.7^1/2×5.0^1/2 = 28.9%.

Citation: Tang KS, Chiu HF, Chen HH, Eng HL, Tsai CJ, Teng HC, Huang CS. Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes. World J Gastroenterol 2005; 11(21): 3250-3254
URL: https://www.wjgnet.com/1007-9327/full/v11/i21/3250.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i21.3250