Expression of E-cadherin in gastric carcinoma and its correlation with lymph node micrometastasis

Table 2 Correlation between the expression of E-cadherin in primary tumors and clinicopathologic characteristics.

Variable	Patients (n)	Expression of E-cadherin
		Negative (%)	Positive (%)	P
Gender
Male	17	7 (41.2)	10 (58.8)
Female	13	7 (53.8)	6 (46.2)	P = 0.713
Age
<50 yr	10	3 (30)	7 (70)
≥R50 yr	20	11 (55)	9 (45)	P = 0.260
Superficial diameter
<5 cm	17	7 (41.2)	10 (58.8)
≥R5 cm	13	7 (53.8)	6 (46.2)	P = 0.713
Tumor location
Upper/middle third	17	8 (47.1)	9 (52.9)
Lower third	13	6 (46.2)	7 (53.8)	P = 1.000
Histologic type
Intestinal	11	2 (18.2)	9 (81.8)
Diffuse	19	12 (63.2)	7 (36.8)	P = 0.026
Depth of invasion
T1/T2	21	8 (38.1)	13 (61.9)
T3/T4	9	6 (66.7)	3 (33.3)	P = 0.236
Histologic differentiation
Well/moderate	13	2 (15.4)	11 (84.6)
Poor	17	12 (70.6)	5 (29.4)	P = 0.004
Lymph node metastasis
Positive	18	12 (66.7)	6 (33.3)
Negative	12	2 (16.7)	10 (83.3)	P = 0.011
Lymphatic invasion
Positive	18	13 (72.2)	5 (27.8)
Negative	12	1 (8.3)	11 (91.7)	P = 0.001