Clinical significance of granuloma in Crohn’s disease

Table 1 Clinical characteristics of patients (mean±SD).

	Patients with granuloma Group I	Patients without granuloma Group II	Significance
Number of patients	25	31	NS
Female/male ratio (No.)	15/10	16/15	NS
Median age (yr)	29.60±11.32	36.46±12.94	NS
Localization
Small bowel only	1 (4%)	4 (12.9%)	NS
Large bowel only	10 (40%)	8 (25.8%)	NS
Small and large bowel	10 (40%)	17 (54.8%)	NS
UGT involvement	4 (16%)	2 (6.4%)	P<0.05
Disease behavior type
Inflammatory	8 (32%)	15 (48.4%)	NS
Stricturing	6 (24%)	9 (29.0%)	NS
Penetrating	11 (44%)	7 (22.6%)	NS
Activity of CD
CDAI	218.9±108.2	144.1±92.5	P = 0.01
Endoscopic scores	6.60±3.53	5.35±4.20	NS

UGT = upper gastrointestinal tract.