Effects of oxymatrine on experimental hepatic fibrosis and its mechanism in vivo

Figure 1 Pathological changes in rats’ liver by H. E. staining. 10×10 A: (Control group): The structure of liver lobules was normal, the size and shape of hepatic cells were normal and distributed centrifugally; B: (CCl₄ group): The normal structure of lobules was destroyed, and pseudolobules were formed. Liver cells swelled and hepatic lobules were encysted and separated by collagen bundles, and associated with infiltration of inflammatory cells; C: (CCl₄+OM group): The normal structure of lobules was also destroyed, pseudolobules formed, and liver cells swelled at a milder extent. The hepatic lobules were encysted and separated by slimmer collagen bundles, with milder infiltration of inflammatory cells.