Increase in neurokinin-1 receptor-mediated colonic motor response in a rat model of irritable bowel syndrome

Figure 1 Motor activities of circular muscle in isolated colonic segments. Motor activities of circular muscle were measured as changes in intraluminal pressure in (A) normal rat colon and (B) IBS rat colon. No difference was observed between groups in the spontaneous rhythmic phasic contraction and in the KCl (60 mmol/L)-induced tonic contraction.