Brief Reports
Copyright ©2005 Baishideng Publishing Group Co.
World J Gastroenterol. Jan 14, 2005; 11(2): 289-292
Published online Jan 14, 2005. doi: 10.3748/wjg.v11.i2.289
Table 1 Frequency distributions and odds ratios of multiple risk factors in 507 HCC cases and 541 controls.
Risk factorVariableHCC case
Control
Crude
Adjusted
P
n (%)n (%)OR (95% CI)OR (95% CI)1
p53 Arg72ProArg563 (55.5)646 (59.7)1
Pro451 (44.5)436 (40.3)1.19 (1.00-1.41)0.05
Arg/Arg145 (28.6)188 (34.8)11
Arg/Pro273 (53.8)270 (49.9)1.31 (1.00-1.73)1.21 (0.82-1.78)0.34
Pro/Pro89 (17.6)83 (15.3)1.39 (0.96-2.01)1.79 (1.06-3.01)0.03
SexFemale73 (14.4)278 (51.4)11
Male434 (85.6)263 (48.6)6.28 (4.66-8.48)4.97 (3.28-7.52)<0.001
Cigarette smokingNo288 (56.8)437 (80.8)11
Yes219 (43.2)104 (19.2)3.20 (2.42-4.21)1.90 (1.19-3.02)<0.01
Alcohol drinkingNo304 (60.0)446 (82.4)11
Yes203 (40.0)95 (17.6)3.13 (2.36-4.16)1.20 (0.75-1.93)0.44
HBsAgNegative137 (27.0)445 (82.3)11
Positive370 (73.0)96 (17.7)12.52 (9.32-16.82)16.83 (11.53-24.56)<0.001
Anti-HCVNegative469 (92.5)527 (97.4)11
Positive38 (7.5)14 (2.6)3.05 (1.63-5.69)7.29 (3.17-16.80)<0.001
Family history2No433 (85.4)532 (98.3)11
Yes74 (14.6)9 (1.7)10.07 (5.00-20.33)9.47 (3.92-22.90)<0.001