Cytotoxic effect of a non-peptidic small molecular inhibitor of the p53-HDM2 interaction on tumor cells

Figure 3 Syl-155-induced apoptosis of tumor cells. All the three cell lines were incubated with 0.2 mL/L DMSO or 10 μg/mL syl-155 for 3 d, stained with PI, and analyzed by flow cytometry to quantitate cells with a subdiploid DNA content. The data were expressed as mean±SD, ^aP<0.05 vs HT1080 group, ^cP<0.05 vs HT1080 group.