Cytotoxic effect of a non-peptidic small molecular inhibitor of the p53-HDM2 interaction on tumor cells

doi:10.3748/wjg.v11.i19.2927

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May 21, 2005 (publication date) through Jul 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 21, 2005; 11(19): 2927-2931
Published online May 21, 2005. doi: 10.3748/wjg.v11.i19.2927

Table 1 Results of cell viability assay (%)¹.

	HT1080	KYSE510	MG63	HELF
Syl-155	40.79	80.61	85.59	87.59
Syc-40	91.23	88.65	90.70	92.51

¹The percentage shown was the VR of three tumor cell lines and one normal cell line after treatment with non-peptidic small compound (syl-155) or negative control compound (syc-40)[21] for 3 d at the concentration of 10 μg/mL. The results were shown as the mean value of three different experiments.

Citation: Li WD, Wang MJ, Ding F, Yin DL, Liu ZH. Cytotoxic effect of a non-peptidic small molecular inhibitor of the p53-HDM2 interaction on tumor cells. World J Gastroenterol 2005; 11(19): 2927-2931
URL: https://www.wjgnet.com/1007-9327/full/v11/i19/2927.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i19.2927