Multigene tracking of quasispecies in viral persistence and clearance of hepatitis C virus

Table 1 Molecular, biochemical, and serological characterization of five HCV primary infections.

Subjects	Samples	Age (yr)/sex	Duration ofinfection(mo)	Genotype	Log10 [HCVRNA]1	HCV RNA	ALT level (nkat/L)2	Result of ELISA
A	A1	30/M	0	3b	7.30	++++	1833.70	-
	A2		6		6.20	+++	583.45	+
	A3		14		5.30	+++	616.79	+
B	B1	28/F	0	3b	7.50	++++	1933.72	-
	B2		6		6.40	+++	1150.23	+
	B3		12		6.90	+++	1533.64	+
C	C1	33/M	0	1b	6.41	+++	683.47	+
	C2		24		5.25	+++	383.41	+
	C3		34		4.16	++	166.70	+
E	E1	20/M	0	1a	6.80	+++	4017.47	-
	E2		3.5		4.20	++	766.82	+
	E3		9		0	–	583.45	+
	E4		24		0	–	400.08	-
F	F1	28/M	0	1b	6.00	++++	3067.28	-
	F2		2		5.60	+++	1066.88	+
	F3		7		0	–	666.80	+
	F4		18		0	–	483.43	-

¹Number of HCV RNA molecules per milliliter plasma. Time zero is the time where the first sample was available; others indicate are times after time zero.

²Normal value, <666.80 nkat/L.