Free radicals and antioxidant systems in reflux esophagitis and Barrett’s esophagus

Figure 3 A: SOD activity decreased with damage. Significant differences were found between patients with esophagitis (grade II-IV) or Barrett’s esophagus and the control group (normal esophageal mucosa) (n = 12-27); B: GSH levels were significantly increased in biopsies from patients with GERD symptoms, esophagitis and duodenal mucosa compared to biopsy samples of normal esophageal mucosa (n = 10-12); C: catalase activity was significantly increased in biopsies from both esophagitis and Barrett’s esophagus patients when compared to normal esophageal mucosa. Duodenal catalase activity was also high (n = 10-12, ^aP<0.05, ^bP<0.01 vs normal esophageal mucosa).