Sulindac induces apoptosis and protects against colon carcinoma in mice

Table 6 Comparison of the density of proliferation and apoptosis with severe dysplasia in the model-agent group, sulindac-preventative group and sulindac-curative group (number/mm²).

Group	n	Proliferative cell density (mean±SD)	Apoptotic cell density (mean±SD)	Ratio (apoptosis/proliferation)
Model	8	159.0±45.9	61.0±24.6	0.38
Preventive	3	155.8±31.9	88.5±14.6	0.57
Curative	5	159.8±22.7	64.2±19.1	0.4

n = number of mice. ^aP<0.05 vs preventive group results with analysis of variance: the difference of proliferation and apoptotic cells density between groups was not statistically significant.