Dynamic expression of pepsinogen C in gastric cancer, precancerous lesions and Helicobacter pylori associated gastric diseases

Table 3 Expression of PGC in H pylori-associated gastric lesions.

astric lesions	n	H pylori positive				n	H pylori negative
		PGC positive expression		PGC over-expression			PGC positive expression		PGC over-expression
		n	Rate (%)	n	Rate (%)	n	Rate (%)	n	Rate (%)
Superficial gastritis	33	33	100.0	28	84.8	25	25	100.0	15	60.0a
Atrophic gastritis	61	4	6.6	0	0.0	30	9	30.0b	1	3.3
Intestinalmetaplasia	61	0	0.0	0	0.0	30	0	0.0	0	0
Dysplasia	40	4	10.0	0	2.5	19	6	31.6	0	0.0
Gastric cancer	58	0	0.0	0	0.0	52	3	5.8	0	0

^aP<0.05, χ² = 0.032; 28/33 vs 15/25;

^bP<0.01, χ² = 0.003; 4/61 vs 9/30.