Inducible nitric oxide synthase, nitrotyrosine and apoptosis in gastric adenocarcinomas and their correlation with a poor survival

Table 2 Univariate and multivariate regression analyses of prognostic indicators for long-term survival.

Factor	Categories	Univariate	Multivariate
		P (Log-rank test)	P (Wald test)	RR (95%CI)
iNOS expression	≥5 scores	0.001	0.012	2.69 (1.54.8)
	≤4 scores
Depth of invasion	pT3, 4	<0.001	0.020	4.11 (1.54.7)
	pT1, 2
Lymph node metastasis	Positive	<0.001	<0.001	5.77 (2.06.6)
	Negative
TNM staging	III, IV	<0.001	0.007	3.94 (1.47.2)
	I, II
Tumor size	≥5 cm	0.043	NS
	<5 cm
Lauren's classification	Diffuse	0.032	NS
	Intestinal
Borrmann classification	3, 4	0.026	NS
	0, 1, 2
Degree of differentiation	Poor	0.023	NS
	Well and moderate
Age (yr)	≤59	0.178
	≥60
Gender	Female	0.201
	Male

≥5 scores: intermediate or high iNOS expression; ≤4 scores: negative or low iNOS expression; RR: relative risk; CI: confidence interval; NS, not significant.